University of Guilan Aquatic Physiology and Biotechnology 2345-3966 6 2 2018 08 23 Effects of vitamin B2 and E on performance of growth, hematological and immunology indices in Caspian Sea salmon (Salmo trutta caspius) Effects of vitamin B2 and E on performance of growth, hematological and immunology indices in Caspian Sea salmon (Salmo trutta caspius) 45 64 3047 10.22124/japb.2018.7532.1167 FA Afshin Ashouri M.Sc. in Fisheries, Lahijan Branch, Islamic Azad University, Lahijan, Iran Hossein Khara Associate Professor in Department of Fisheries, Lahijan Branch, Islamic Azad University, Lahijan, Iran Mohaddeseh Ahmadnezhad Assistant Professor in Inland Waters Aquaculture Research Center, Iranian Fisheries Science Research Institute, Agricultural Research Education and Extension Organization (AREEO), Bandar Anzali, Iran Journal Article 2017 05 16 The Caspian Sea salmon (<em>Salmo trutta caspius</em>) is anadromous fish which has economic value and high popularity. In this study, the effects of vitamin E and B₂ were investigated on growth performance, hematological and immunology parameters. This study does on 750 fish. Fishes with an initial weight of 20±3g were divided into 10 groups, one was the control group and other groups received different doses of vitamin E and B₂. 15, 20, 25 mg/Kg vitamin B₂, 100, 200 300 mg/Kg vitamin E and 15+100, 20+200 and 25+300 mg/Kg mixture of vitamin B₂+E in T1 to T9, respectively. Significant differences were observed in final weight and length of different treatments (P<0.05). The lowest weight and length increment was seen in the control group. Also, the best FCR and the highest SGR, GR, BWI, and CF were observed in T8, the largest WBC, RBC, IgM, and lysozyme were measured in T9 and the largest MCHC, MCH, MCV, Hb and total immunoglobulin were recorded in control group. The best performance was obtained in T8 (20B₂+200E). Overall results showed that adding the mixture of 2 vitamins improve growth and performances of the immune system and has larger effects on growth. The Caspian Sea salmon (<em>Salmo trutta caspius</em>) is anadromous fish which has economic value and high popularity. In this study, the effects of vitamin E and B₂ were investigated on growth performance, hematological and immunology parameters. This study does on 750 fish. Fishes with an initial weight of 20±3g were divided into 10 groups, one was the control group and other groups received different doses of vitamin E and B₂. 15, 20, 25 mg/Kg vitamin B₂, 100, 200 300 mg/Kg vitamin E and 15+100, 20+200 and 25+300 mg/Kg mixture of vitamin B₂+E in T1 to T9, respectively. Significant differences were observed in final weight and length of different treatments (P<0.05). The lowest weight and length increment was seen in the control group. Also, the best FCR and the highest SGR, GR, BWI, and CF were observed in T8, the largest WBC, RBC, IgM, and lysozyme were measured in T9 and the largest MCHC, MCH, MCV, Hb and total immunoglobulin were recorded in control group. The best performance was obtained in T8 (20B₂+200E). Overall results showed that adding the mixture of 2 vitamins improve growth and performances of the immune system and has larger effects on growth. https://japb.guilan.ac.ir/article_3047_4000e0702d32d1bdc5ea5e91aa81ebbf.pdf