Effects of irradiated Ergosan on growth performance, serum biochemical parameters and skin mucosal immune responses in crucian carp (Carassius carassius)

Document Type : Research Paper


1 Associate Professor in Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran

2 Associate Professor in Department of Veterinary and Animal Science, Nuclear Agriculture Research School, Nuclear Science and Technology Research Institute, Karaj, Iran

3 Associate Professor in Department of Food Hygiene and Aquatic Animals, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran

4 M.Sc. in Abzian Nil Pars Co., Tehran, Iran

5 Ph.D. Student in Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran


The present study was designed to evaluate the effects of irradiated and non-irradiated Ergosan on growth performance, serum biochemical parameters and skin mucosal immune responses in crucian carp (Carassius carassius). Fish with a mean weight of 9.16±0.36g were randomly distributed among nine aquaria in triplicates and fed diets containing irradiated Ergosan at 30 kGy (1g.kg-1), non-irradiated Ergosan (1g.kg-1), or diet without any additives (control) for 40 days. Results showed that fish fed with irradiated and non-irradiated Ergosan had higher growth performance than the control (P<0.05). Mucosal biochemical parameters, including protein, glucose, cholesterol and triglyceride, were not altered by feeding treatment diets compared to the control (P>0.05). Digestive enzyme activities, including intestinal alkaline phosphatase and protease, increased with both Ergosan-treated diets, especially with irradiated Ergosan to the control (P<0.05). Skin mucosal lysozyme, alkaline phosphatase, and protease activities, also enhanced after administration of irradiated and non-irradiated Ergosan compared to the control (P<0.05). This study suggests that the supplementation of Ergosan, especially in irradiated form, could improve the growth performance, some digestive enzyme activities, and skin mucosal responses in crucian carp.


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