Evaluating the effectiveness of seaweed, Sargassum ilicifolium, extract and animal extract of brittle star, Ophiocoma scolopendrina, in the amount of ultraviolet ray absorption by cerium oxide nanoparticles

Document Type : Research Paper

Authors

1 Ph.D. Student in Marine Biology, Department of Marine Biology, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, Iran

2 Associate Professor in Department of Marine Biology, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, Iran

3 Professor in Department of Biology, Faculty of Sciences, University of Qom, Qom, Iran

4 Associate Professor in Department of Chemistry, Faculty of Sciences, University of Hormozgan, Bandar Abbas, Iran

10.22124/japb.2024.25709.1516

Abstract

Today, green synthesis methods of nanoparticles are increasing. This research was aimed at investigating the synthesis of cerium oxide nanoparticles (CeO2-NPs) using Sargassum ilicifolium and Ophiocoma scolopendrina extracts and confirming the protective effect as well as the stability of the cream formulation with cerium oxide nanoparticles against UVR. The obtained products were identified using XRD, TEM, SEM and UV-Vis. Then cream samples were prepared with concentrations of 0, 0.5, 2, 4 and 8% CeO2-NPs. Based on the results, the nanoparticles were spherical in shape and had a cubic crystal structure with a size of about 10-12 nm. The peak between 290-320nm corresponded to UVB and the absorption spectrum of the synthesized CeO2-NPs showed absorption peaks at 317 and 315nm wavelengths. Formulation F5 of sunscreen containing nanoparticle synthesized from S. ilicifolium with SPF 25 and critical wavelength (λC) 380.4nm showed the highest protection factor. According to the star rating, it had four stars. The cream formulation was completely homogeneous and stable in the cooling-heating cycle. Also, the pH was close to the pH of human skin. The results of MTT test to investigate the toxicity of CeO2-NPs on HFF cell line, indicated that the treated cells did not show significant toxicity compared to the control. According to the results of this study, CeO2 nanoparticles have the necessary conditions for progress in solar protection technology.

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