Evaluating the effectiveness of cerium oxide nanoparticles synthesized with seaweed extract (Sargassum ilicifolium) and brittle star animal extract (Ophiocoma scolopendrina) in absorbing ultraviolet

Document Type : Research Paper


1 Hormozgan University

2 Department of Marine Biology, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, Iran /Department of Modern Technologies,, Mangrove Forest Research Center, Univerity of Hormozgan

3 qom University

4 Department of Chemistry, College of Sciences, University of Hormozgan, Bandar Abbas 7916193145, Iran



Today, green synthesis methods of nanoparticles are increasing. This research was aimed at investigating the synthesis of cerium oxide nanoparticles using Sargassum ilicifolium and Ophiocoma scolopendrina extracts and confirming the protective effect as well as the stability of the cream formulation with cerium oxide nanoparticles against UVR. The obtained products were identified using XRD, TEM, SEM and UV-vis. Based on the obtained results, the nanoparticles are spherical in shape and have a cubic crystal structure with a size of about 10-12 nm. The peak between 290-320 nm corresponds to UVB and the absorption spectrum of the synthesized CeO2-NPs showed absorption peaks at 317 and 315 nm wavelengths. Formulation F5 of sunscreen containing nanoparticle synthesized from algae with spf = 25 and critical wavelength λ = 380.4 showed the highest protection factor. According to the star rating, it has four stars. The cream formulation was completely homogeneous and stable in the cooling-heating cycle. Also, the pH was close to the pH of human skin.MTT method was used to investigate the toxicity of CeO2-NPs on HFF cell line and the results indicated that the treated cells did not show significant toxicity compared to the control.


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